Clinical Study

The Phenotype of Circulating Follicular-Helper T Cells in Patients with Rheumatoid Arthritis Defines CD200 as a Potential Therapeutic Target

Figure 4

Relationship between CD200 expression on TFH cells, treatment, and disease activity. (a) The % of TFH cells expressing CD200 in patients being treated with anti-TNFα therapy was significantly increased compared with patients not on anti-TNFα therapy ( ). The mean DAS of patients receiving anti-TNFα therapy was 4.679, compared with 4.418 in patients who were not ( ). Each spot represents an individual patient, and the mean ± SEM are shown. (b) Correlation between TFH cell CD200 expression and DAS-28 score ( ).
948218.fig.004a
(a)
948218.fig.004b
(b)