Downregulation of Hlx Closely Related to the Decreased Expressions of T-bet and Runx3 in Patients with Gastric Cancer May Be Associated with a Pathological Event Leading to the Imbalance of Th1/Th2
Figure 3
The levels of IFN-γ and IL-4 in serum and the correlation between expression levels of Hlx and T-bet/GATA3 mRNA from gastric carcinoma sufferers. In serum of patients, the level of IFN-γ was obviously decreased (), but the level of IL-4 was enhanced (), compared with healthy control (a) and (b). The vertical coordinate indicates the T-bet/β-actine ratio (c) or GATA3/β -actine ratio (d), and horizontal coordinate indicates the Hlx/β-actine ratio. There was a significantly positive correlation between Hlx and T-bet (, ), and a negative correlation between Hlx and GATA3 (, ).
