Perinatal Programming of Childhood Asthma: Early Fetal Size, Growth Trajectory during Infancy, and Childhood Asthma Outcomes

Table 2

Summary of asthma and allergy outcomes in the context of changing growth trajectory during early pregnancy.

First-second trimester	Increased rate of growth			Reduced rate of growth
	Asthma symptoms	Atopy	Lung function	Asthma symptoms	Atopy	Lung function
Southampton 3 years		Increased skin prick positivity		Increased nonatopic wheeze
Aberdeen 5 years	Increased asthma		Reduced FEV1, FVC, FEF25−75			Reduced FEV1
Aberdeen 10 years	Increased asthma	Increased hayfever	Reduced FEF25−75	Increased asthma	Reduced eczema	Reduced FVC