Association of Intrarenal B-Cell Infiltrates with Clinical Outcome in Lupus Nephritis: A Study of 192 Cases
Table 1
Demographics, clinical characteristics, and laboratory analysis of LN patients.
LN-B-cell
LN-non-B-cell
value
Sex (male/female)
17/101
8/66
0.513
Age (years)
34 ± 13
33 ± 13
0.526
SLE duration (months)
57 ± 60
43 ± 63
0.294
LN duration (months)
25 ± 37
26 ± 49
0.852
SLEDAI
14 ± 6
13 ± 5
0.042
Proteinuria (g/24 h)
3.13 ± 2.97
2.69 ± 2.56
0.311
Blood urea nitrogen (mmol/L)
10.43 ± 7.67
6.24 ± 3.40
0.000
Serum creatinine (μmol/L)
89.91 ± 66.89
59.75 ± 22.05
0.000
Serum C3 (g/L)
0.51 ± 0.21
0.54 ± 0.26
0.427
Serum C4 (g/L)
0.082 ± 0.049
0.084 ± 0.076
0.827
Anti-dsDNA (positive/negative)†
72/11
44/9
0.506
dsDNA antibodies were not detected in 35 patients in the LN-B-cell group and 21 patients in LN-non-B-cell group. SLEDAI: systemic lupus erythematosus disease activity index; SLE: systemic lupus erythematosus; LN: lupus nephritis; anti-dsDNA: anti-double-stranded DNA antibody.
