Journal of Immunology Research / 2012 / Article / Fig 8

Clinical Study

Immune Modulation in Primary Vaccinia virus Zoonotic Human Infections

Figure 8

Aspects of the immune responses in mice infected or not with zoonotic Vaccinia virus. Peripheral blood mononuclear cells (PBMCs) from mice either infected with a zoonotic Vaccinia virus isolate or noninfected were cultured for 72 hours in the presence of UV-inactivated VACV. After incubation, cells were labeled with specific antibodies and analyzed by flow cytometry. (a) Percentage of total monocytes (CD14+); (b) percentage of CD4+ T lymphocytes expressing the CD25 surface activation marker; (c) percentage of CD8+ T lymphocytes. Bars represent the mean results from 10 animals. Error bars and values are indicated.

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