Potential Use of Bisphosphonates in Invasive Extramammary Paget’s Disease: An Immunohistochemical Investigation
Figure 1
CD8, granulysin, TIA-1, and perforin in noninvasive and invasive EMPD. Paraffin-embedded tissue samples from patients with invasive and noninvasive EMPD were deparaffinized and stained using a combination of anti-CD8 Ab ((a) and (b)) and anti-granulysin Ab ((c) and (d)), anti-TIA-1 Ab ((e) and (f)) or antiperforin Ab ((g) and (h)). Noninvasive EMPD: (a), (c), (e), and (g); invasive EMPD: (b), (d), (f), and (h). Original manifestation: 200. Sections were developed with liquid permanent red.