Low-Dose Amphotericin B and Murine Dialyzable Spleen Extracts Protect against Systemic Candida Infection in Mice

Figure 2

Representative histological features of kidneys from mice with systemic candidiasis. Mice were infected with 5 × 10⁵ CFU of Ca07-387 and were left untreated (a), (b), (f), and (g) or were treated with 10 pg mDSE (c) and (h), 0.1 mg/kg AmB (d) and (i), or mDSE and AmB (e) and (j). Kidney sections were taken on days 2 (a) and (f) and 10 (b)–(e), (g)–(j) after infection and stained with HE (a)–(e) or with GG (f)–(j).

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