Journal of Immunology Research / 2013 / Article / Fig 1

Clinical Study

Autologous CIK Cell Immunotherapy in Patients with Renal Cell Carcinoma after Radical Nephrectomy

Figure 1

(a) Trials and treatments of the two groups sectionalization. (b) Treatment protocol: cytokine-induced killer (CIK) cell transfusion cycle. Peripheral blood mononuclear cells (PBMCs) were cultured for 14 days in the presence of recombinant human interferon gamma (rhIFN-γ), recombinant human interleukin-2 (rhIL-2), and anti-CD3 monoclonal antibody before transfusion for two consecutive days. Patients were injected with rhIL-2 subcutaneously at 1 mU/day for 10 days immediately after transfusion for 10 days. Thymopentin was injected intramuscularly for 7 days before the next PBMC collection and culturing.

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