Review Article

Collagen XVII: A Shared Antigen in Neurodermatological Interactions?

Table 1

Epidemiological studies linking bullous pemphigoid and neurological morbidity.

ReferenceCountry of studyType of studyNumber of BP cases in studyNeurological disorders associated to BP

Foureur et al., 2001 [36]FranceRetrospective case control46Senile dementia/Alzheimer
Cerebral stroke

Stinco et al., 2005 [45]ItalyRetrospective238Multiple sclerosis
Parkinson’s disease

Cordel et al., 2007 [37]FranceRetrospective341Dementia
Cerebral stroke
Parkinson’s disease or parkinsonism

Jedlickova et al., 2010 [38]Czech RepublicRetrospective case control89Dementia
Cerebral stroke

Taghipour et al., 2010 [39]UKRetrospective case control90Cerebrovascular disease
Dementia

Langan et al., 2011 [40]UKRetrospective population based case-control868Dementia
Parkinson’s disease
Stroke
Epilepsy

Bastuji-Garin et al., 2011 [41]FranceProspective case control201Severe cognitive impairment (MMSE < 17)
Parkinsons’ disease
Uni- or bipolar disorder
Long-term neuroleptic drug use

Chen et al., 2011 [42]TaiwanRetrospective population based case control3485Dementia
Stroke
Schizophrenia
Epilepsy
Parkinson’s disease