Baicalin Inhibits IL-17-Mediated Joint Inflammation in Murine Adjuvant-Induced Arthritis
Baicalin inhibits ankle joint inflammation injury in adjuvant-induced arthritis mice. Adjuvant-induced arthritis mice were injected intraperitoneally daily with 100 mg/kg Baicalin or phosphate-buffered saline (vehicle control) for 1 week. Hematoxylin and eosin staining of control mice (a), adjuvant-induced arthritis mice with vehicle control treatment (b), and adjuvant-induced arthritis mice with Baicalin treatment (c). Further magnification of the black-bordered box showed the typical inflammatory injuries in control mice (d), adjuvant-induced arthritis mice with vehicle control treatment (e), and adjuvant-induced arthritis mice with Baicalin treatment (f). (g) Histopathological scores of the joint tissues ( for each group).
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