Journal of Immunology Research / 2013 / Article / Fig 3

Research Article

Upregulated MicroRNA-155 Expression in Peripheral Blood Mononuclear Cells and Fibroblast-Like Synoviocytes in Rheumatoid Arthritis

Figure 3

Constitutive expression and inductive expression of miR-155 in RA-FLS. (a) Overexpression of miR-155 in cultured RA-FLS ( ) compared to OA-FLS ( , , 1.79 ± 1.94, 0.11 ± 0.17, resp.). (b) Trend of up-regulation by TNF-α on RA-FLS ( ). The up-regulation of miR-155 upon stimulation of RA-FLS, as compared with that in unstimulated control cultures, was about 1.87-fold with TNF-α stimulation, after 24 hours ( ); 2.22-fold after 48 hours ( ); and 1.38-fold after 72 hours ( ).

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