Mesoporous Silicon Microparticles Enhance MHC Class I Cross-Antigen Presentation by Human Dendritic Cells
The microparticles are internalized into dendritic cells (DC). (a) Photographs show control cells (MDDCs) or with internalized unloaded (MDDCs-MSMPs) or peptide loaded (MDDCs-MSMPs-CEFpp) microparticles. After 24 h of incubation the cells are aggregated, and the particles are inside vacuoles ((b)-(c) and insert). Trypan blue dye was used to determine the percentage of live MDDCs relative to a nontreatment control following 24 h incubation with MSMPs (d). *.
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