Human Polyomavirus Reactivation: Disease Pathogenesis and Treatment Approaches

Figure 2

Schematic diagram illustrating the organisation of the dsDNA genome of BK virus. The open reading frames are represented by arrows with alternative splicing events highlighted by dashed lines. The origin of replication (ORI) within the noncoding control region (NCCR), from which transcription of early and late mRNAs proceeds, is indicated. The agnoprotein and truncated T antigen genes have not been described in all polyomaviruses.