Immunophenotyping in BK Virus Allograft Nephropathy Distinct from Acute Rejection

Table 4

Proportions of infiltrating lymphocytes in HLA-DR-positive and HLA-DR-negative BKVN patients.

	HLA-DR < 10% (𝑛=11)	HLA-DR ≥ 10% (𝑛=11)	𝑃  value
CD3/total (%)	36.8 (30.7–43.1)	35.2 (30.5–44.8)	0.847
CD4/total (%)	19.9 (17.7–22.4)	19.9 (16.4–24.9)	0.652
CD8/total (%)	17.3 (13.8–23.1)	18.6 (13.7–22.4)	0.699
CD20/total (%)	13.1 (4.2–17.9)	16.2 (11.5–25.8)	0.217
CD68/total (%)	52.4 (35.5–55.8)	45.2 (39.6–49.0)	0.309
CD3/CD68	0.76 (0.60–1.09)	0.75 (0.63–1.00)	0.844
CD3/CD20	3.23 (1.61–9.70)	2.16 (1.48–3.56)	0.178

BKVN: BK virus nephropathy; HLA: human lymphocyte antigen.