Induction of Antinuclear Antibodies by De Novo Autoimmune Hepatitis Regulates Alloimmune Responses in Rat Liver Transplantation
Figure 1
The prolongation of allograft survival by the transient induction of de novo autoimmune hepatitis. (a) The DA liver allograft survival of DA-LEW OLT with Con A injection () was significantly prolonged (, log-rank test) compared with the survival in the control PBS group (). (b) Paraffin sections of naïve and OLT livers at rejection (day 7) or acceptance (>200 days) were stained with hematoxylin and eosin. The data are representative examples of three (naïve and OLT at day 7) or two (>200 days) individual liver sections (40x magnification, bar = 20 μm).
