The Diagnostic Value of Transcription Factors T-bet/GATA3 Ratio in Predicting Antibody-Mediated Rejection

Table 1

Clinical characteristics of patients participating in this study.

Characteristics	C4d(+) ABMR (𝑛=11)	C4d(−) ABMR (𝑛=5)	TCMR (𝑛=10)	𝑃 value
Gender, male (%)	2 (18.2)	4 (80.0)	9 (90.0)	0.002
Age (years)	40.18±8.38	39.60±12.95	38.80±11.74	0.957
Donor age (years)	44.00±9.89	44.90±11.92	41.20±10.84	0.771
Positive pretransplant PRA (𝑛)	0	0	0	—
Previous transplant	0	0	0	—
Cold ischemic time (h)	8.18±1.40	8.40±1.14	8.93±1.57	0.866
Warm ischemic time (min)	6.36±1.20	6.20±1.30	6.80±1.31	0.623
Induction with IL-2R antibody, 𝑛 (%)	11 (100)	5 (100)	10 (100)	—
Baseline immunosuppressants				0.118
MMF + Tac + Pred	11 (100)	5 (100)	10 (100)	—
Time of biopsy after Tx (day)	6.36±5.16	3.40±0.89	11.50±4.90	0.008

PRA: panel-reactive antibody; IL: interleukin; MMF: mycophenolate mofetil; Pred: prednisolone; Tac: tacrolimus; Tx: transplantation; ABMR: antibody-mediated rejection; TCMR, T-cell-mediated rejection.