Research Article

B Epitope Multiplicity and B/T Epitope Orientation Influence Immunogenicity of Foot-and-Mouth Disease Peptide Vaccines

Figure 2

Antibody responses to FMDV in sera analyzed by neutralization assay at day 39 postimmunization. The VNT titers determined in each group of mice were expressed as the reciprocal ( ) of the last dilution able to neutralize 100 TICD50 of homologous virus. Animals with VNT ≥ 1 are considered seropositive. Each symbol represents the value for an individual animal. Horizontal lines indicate the mean value for each group of animals. Statistical differences between B2T group and the others are indicated by values.
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