B Epitope Multiplicity and B/T Epitope Orientation Influence Immunogenicity of Foot-and-Mouth Disease Peptide Vaccines
Figure 4
Systemic (serum) and local (nasal) IgA antibody responses to FMDV determined by ELISA at day 39 postimmunization. (a) IgA antibody titers against FMDV. Endpoint titers were expressed as described in Figure 3. Each symbol represents the value for an individual mouse. Horizontal lines indicate the mean value for each group of animals. (b) IgA antibody titers against FMDV determined in nasal fluids. Titers are expressed as the OD at 450 nm value obtained using a 1 : 10 dilution.
