Role of Toll-Like Receptor 4 on Lupus Lung Injury and Atherosclerosis in LPS-Challenge ApoE^−/− Mice

Table 2

Intima-media thickness of brachiocephalic artery and plaque area of aortic sinus in ApoE^−/− and wild-type mice.

	ApoE^−/− (𝑛=10)		Wild-type mice (𝑛=10)
	IMT (𝜇m)	Plaque area (%)	IMT (𝜇m)	Plaque area (%)
NS	42.1±1.9^$	20.2±2.3	20.5±3.6	Not arise
LPS	75.8±5.8^∗$	22.1±4.6	39.7±7.4^∗	Not arise
LPS + TAK-242	55.4±6.4^$#	20.7±3.2	27.3±4.1^#	Not arise

^∗𝑃<0.05  versus  corresponding NS group, ^#𝑃<0.05  versus  corresponding LPS group, and ^$𝑃<0.05  versus  wild-type mice. IMT: intima-media thickness; NS: physiological saline; LPS: lipopolysaccharide; TAK-242: resatorvid.