Molecular Profiling of Acute and Chronic Rejections of Renal Allografts
Table 2
Significant differences between failed and survived grafts after chronic rejection (both CAMR and CTCMR). Only variables that reach statistical significance are listed.
Failed grafts ()
Survived grafts ()
P
sCr at Bx [µmol/L]
298.1 [197.3–456.8]
193.5 [91.2–485.6]
0.005
eGFR at Bx [mL/s/1.73 m2]
0.28 [0.18–0.37]
0.47 [0.13–0.98]
0.008
Proteinuria at Bx [g/day]
3.47 [0.61–12.58]
0.47 [0–2.35]
0.001
CCL19
1.5197 [0.1042–11.1551]
8.6061 [0.4848–82.2367]b
0.044
CDC20
2.4168 [1.8262–3.1978]
0.9337 [0.4203–3.0410]
0.007
CXCL6
2.6814 [0.3292–14.7608]a
0.4933 [0.0000–1.9457]b
0.039
DIABLO
1.9110 [1.6832–6.2070]
1.3873 [0.7627–2.0413]
0.018
GABRP
3.5970 [0.5333–13.8507]a
0.2527 [0.0000–7.2719]b
0.013
KIAA0101
5.9674 [2.8230–17.7875]
3.7627 [0.2982–6.2863]
0.032
ME2
1.7962 [1.0032–2.5815]
1.1111 [0.6937–2.5290]
0.038
MMP7
1.4519 [0.8888–4.4876]
0.4838 [0.0026–4.3613]
0.004
NFATC4
2.3609 [0.8072–7.0016]c
0.7314 [0.0000–2.3032]b
0.012
TGFB3
1.1726 [0.1405–2.0126]c
0.1292 [0.0000–15.6462]d
0.034
TRADD
2.3305 [0.9925–16.0450]c
9.6845 [3.1361–45.8793]e
0.037
Variables are presented as median (min–max).
an = 6.
bn = 14.
cn = 5.
dn = 12.
en = 10.
