Comparing Effects of BK Virus Agnoprotein and Herpes Simplex-1 ICP47 on MHC-I and MHC-II Expression
Figure 3
(a) HLA-ABC and -DR surface expression in transiently transfected RPTECs. Cells were cotransfected with pEGFP-N1 and either pCMV-agno or pCMV-ICP47 at a 1 : 10 ratio. pEGFP-N1 alone (mock, ) or together with pCMV-agno () or with pCMV-ICP47 as described above. MFI: mean fluorescence intensity. (b) HLA-ABC and -DR surface expression in transiently transfected UTA-6. UTA-6 cells were cotransfected with pEGFP-N1 and either pCMV-agno or pCMV-ICP47 at a 1 : 10 ratio. pEGFP-N1 alone (mock, ) or together with pCMV-agno () or with pCMV-ICP47 as described above. MFI: mean fluorescence intensity.
