Interleukin-15 (IL-15) and Anti-C1q Antibodies as Serum Biomarkers for Ectopic Pregnancy and Missed Abortion

Table 1

Anti-C1q antibody concentrations in 60 women with failed pregnancies, including 30 women with ectopic pregnancy (EP) and missed abortion (MA) and 33 women with intrauterine pregnancy (IUP). The nonparametric Kruskal-Wallis test was used to identify differences among EP, MA, and viable IUP. To perform pairwise comparisons between groups Mann-Whitney test was conducted determining as critical value for significance P = 0.0167 after using Bonferroni correction which determined as critical value of significance for each (Mann-Whitney) test the value 0.0167. Therefore anti-C1q antibody levels are not helpful in differentiating between the three groups since as shown in Table 1 there is no P value <0.167.

		Failed pregnancies (MA and EP)			Normal	P value
Anti-C1q	Median	30.92			38.95	0.018 *
	IQR	17.89–40.79			28.95–59.01
		Pregnancy outcome
		IUP	MA	EP
Anti-C1q	Median	38.95	31.97	18.82		0.045 **
	IQR	28.95–59.01	23.95–39.47	16.32–40.79

∗Mann-Whitney test.
**Kruskal-Wallis test.