Clinical Study
A Clinical Analysis of Risk Factors for Interstitial Lung Disease in Patients with Idiopathic Inflammatory Myopathy
Table 1
Univariable analysis of risk factors for ILD in patients with IIM.
| | Items | With ILD () | Without ILD () | value |
| | Mean age at diagnosis (years) | | | n.s. | | Male : female | 24 : 59 | 13 : 38 | n.s. | | Disease duration (months) | | | n.s. | | Proximal muscle weakness | 59 (71.1%) | 45 (88.2%) | <0.05 | |
Myosalgia | 39 (47.0%) | 25 (49.0%) | n.s. | | Arthritis/arthralgia | 45 (54.2%) | 9 (17.6%) | <0.05 | | Mechanic’s hand | 14 (16.9%) | 1 (2.0%) | <0.05 | | Raynaud’s phenomenon | 30 (36.1%) | 1 (2.0%) | <0.05 | | Gottron’s sign | 33 (39.8%) | 16 (31.4%) | n.s. | | Heliotrope rash | 37 (44.6%) | 10 (19.6%) | <0.05 | | Fever | 36 (43.4%) | 11 (21.6%) | <0.05 | | Elevated ESR | 50 (60.2%) | 18 (35.3%) | <0.05 | | Elevated CRP | 46 (55.4%) | 16 (31.4%) | <0.05 | | Elevated CK | 62 (74.7%) | 47 (92.2%) | <0.05 | | ANA (+) | 57 (68.7%) | 34 (66.7%) | n.s. | | Anti-SS-A antibody (+) | 24 (28.9%) | 11 (21.6%) | n.s. | | Anti-Jo-1 antibody (+) | 17 (20.5%) | 3 (5.9%) | <0.05 |
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IIM: idiopathic inflammatory myopathies; ILD: interstitial lung disease; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; CK: creatine kinase, ANA: antinuclear antibody; n.s.: not significant.
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