Clinical Phenotypes of Patients with Anti-DFS70/LEDGF Antibodies in a Routine ANA Referral Cohort

Table 1

Correlation between DFS and other IIF patterns and anti-DFS70 antibodies by ELISA and CIA.

Assay	DFS pattern	Other patterns	Positive % agreement*	Negative % agreement*	𝑃
DFS70 CIA	91/100 (91.0%)	3/100 (3.0%)	91.0% (83.6–95.8%)	97.0% (91.5–99.4%)	𝑃<0.0001
ANA ELISA	35/100 (35.0%)	67/100 (67.0%)	67.0% (56.9–76.1%)	65.0% (54.8–74.3%)	𝑃<0.0001

*Positive and negative percent agreements were calculated based on the target cohort: For DFS70 CIA the target cohort is the group of samples with DFS pattern and the control cohort is the group of samples with other ANA patterns; for ANA ELISA the target cohort is the group of samples with other ANA patterns and the control cohort is the group of samples with DFS patterns.