BCG and BCG/DNAhsp65 Vaccinations Promote Protective Effects without Deleterious Consequences for Experimental Autoimmune Encephalomyelitis

Table 1

Morphometric analysis of perivascular inflammatory infiltrate in the brain and lumbar spinal cord samples from rats immunized with BCG alone or associated with pVAXhsp65 before EAE induction.

	Brain; 𝑛=4	Lumbar spinal cord; 𝑛=4
	(μm^2 of mononuclear infiltrate/mm^2of organ section)^†
Control EAE	3.55±0.72	6.56±2.72
BCG EAE	1.17±0.38^∗	7.38±2.53
BCG pVAXhsp65 EAE	1.50±0.71^∗	4.46±0.79

^∗𝑃<0.05 versus control EAE.
^†Morphometric analysis was done in 5-micron thick sections after haematoxylin and eosin stain using a Nikon Microphot-FXA optical microscope connected to a computer and employing the KS300 software.