Table of Contents Author Guidelines Submit a Manuscript
Clinical and Developmental Immunology
Volume 2013 (2013), Article ID 721782, 8 pages
http://dx.doi.org/10.1155/2013/721782
Clinical Study

Increased Numbers of NK Cells, NKT-Like Cells, and NK Inhibitory Receptors in Peripheral Blood of Patients with Chronic Obstructive Pulmonary Disease

1Department of Respiratory Medicine, The First Hospital, Jilin University, Changchun 130021, China
2Department of the Central Laboratory, The Second Part of the First Hospital, Jilin University, Changchun 130021, China

Received 11 January 2013; Revised 24 June 2013; Accepted 26 June 2013

Academic Editor: G. Opdenakker

Copyright © 2013 Ying Tang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. D. Lopez, C. D. Mathers, M. Ezzati, D. T. Jamison, and C. J. Murray, “Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data,” The Lancet, vol. 367, no. 9524, pp. 1747–1757, 2006. View at Publisher · View at Google Scholar · View at Scopus
  2. K. F. Rabe, S. Hurd, A. Anzueto et al., “Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary,” The American Journal of Respiratory and Critical Care Medicine, vol. 176, no. 6, pp. 532–555, 2007. View at Publisher · View at Google Scholar · View at Scopus
  3. L. G. Miller, G. Goldstein, M. Murphy, and L. C. Ginns, “Reversible alterations in immunoregulatory T cells in smoking. Analysis by monoclonal antibodies and flow cytometry,” Chest, vol. 82, no. 5, pp. 526–529, 1982. View at Google Scholar · View at Scopus
  4. L. C. Ginns, P. D. Goldenheim, L. G. Miller et al., “T-lymphocyte subsets in smoking and lung cancer. Analysis by monoclonal antibodies and flow cytometry,” The American Review of Respiratory Disease, vol. 126, no. 2, pp. 265–269, 1982. View at Google Scholar · View at Scopus
  5. J. Gupta, D. Chattopadhaya, D. P. Bhadoria et al., “T lymphocyte subset profile and serum alpha-1-antitrypsin in pathogenesis of chronic obstructive pulmonary disease,” Clinical and Experimental Immunology, vol. 149, no. 3, pp. 463–469, 2007. View at Publisher · View at Google Scholar · View at Scopus
  6. A. Di Stefano, G. Turato, P. Maestrelli et al., “Airflow limitation in chronic bronchitis is associated with T-lymphocyte and macrophage infiltration of the bronchial mucosa,” The American Journal of Respiratory and Critical Care Medicine, vol. 153, no. 2, pp. 629–632, 1996. View at Google Scholar · View at Scopus
  7. T. C. O'Shaughnessy, T. W. Ansari, N. C. Barnes, and P. K. Jeffery, “Inflammation in bronchial biopsies of subjects with chronic bronchitis: inverse relationship of CD8+ T lymphocytes with FEV1,” The American Journal of Respiratory and Critical Care Medicine, vol. 155, no. 3, pp. 852–857, 1997. View at Google Scholar · View at Scopus
  8. C. H. Bosken, J. Hards, K. Gatter, and J. C. Hogg, “Characterization of the inflammatory reaction in the peripheral airways of cigarette smokers using immunocytochemistry,” The American Review of Respiratory Disease, vol. 145, no. 4, part 1, pp. 911–917, 1992. View at Google Scholar · View at Scopus
  9. F. Colucci, M. A. Caligiuri, and J. P. Di Santo, “What does it take to make a natural killer?” Nature Reviews Immunology, vol. 3, no. 5, pp. 413–425, 2003. View at Publisher · View at Google Scholar · View at Scopus
  10. S. Johansson, L. Berg, H. Hall, and P. Höglund, “NK cells: elusive players in autoimmunity,” Trends in Immunology, vol. 26, no. 11, pp. 613–618, 2005. View at Publisher · View at Google Scholar · View at Scopus
  11. A. G. Baxter and M. J. Smyth, “The role of NK cells in autoimmune disease,” Autoimmunity, vol. 35, no. 1, pp. 1–14, 2002. View at Publisher · View at Google Scholar · View at Scopus
  12. C. E. Andoniou, S. L. H. van Dommelen, V. Voigt et al., “Interaction between conventional dendritic cells and natural killer cells is integral to the activation of effective antiviral immunity,” Nature Immunology, vol. 6, no. 10, pp. 1011–1019, 2005. View at Publisher · View at Google Scholar · View at Scopus
  13. T. Mallevaey, A. J. Clarke, J. P. Scott-Browne et al., “A molecular basis for NKT cell recognition of CD1d-self-antigen,” Immunity, vol. 34, no. 3, pp. 315–326, 2011. View at Publisher · View at Google Scholar · View at Scopus
  14. A. Prieto, E. Reyes, E. D. Bernstein et al., “Defective natural killer and phagocytic activities in chronic obstructive pulmonary disease are restored by glycophosphopeptical (Inmunoferón),” The American Journal of Respiratory and Critical Care Medicine, vol. 163, no. 7, pp. 1578–1583, 2001. View at Google Scholar · View at Scopus
  15. R. A. Urbanowicz, J. R. Lamb, I. Todd, J. M. Corne, and L. C. Fairclough, “Altered effector function of peripheral cytotoxic cells in COPD,” Respiratory Research, vol. 10, article 53, 2009. View at Publisher · View at Google Scholar · View at Scopus
  16. E. Vivier, D. H. Raulet, A. Moretta et al., “Innate or adaptive immunity? The example of natural killer cells,” Science, vol. 331, no. 6013, pp. 44–49, 2011. View at Publisher · View at Google Scholar · View at Scopus
  17. C. Watzl and E. O. Long, “Signal transduction during activation and inhibition of natural killer cells,” Current Protocols in Immunology, vol. 11, p. 11.9B, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. C. A. Biron and L. Brossay, “NK cells and NKT cells in innate defense against viral infections,” Current Opinion in Immunology, vol. 13, no. 4, pp. 458–464, 2001. View at Publisher · View at Google Scholar · View at Scopus
  19. C. A. Stewart, E. Vivier, and M. Colonna, “Strategies of natural killer cell recognition and signaling,” Current Topics in Microbiology and Immunology, vol. 298, pp. 1–21, 2005. View at Google Scholar · View at Scopus
  20. M. López-Botet, M. Llano, F. Navarro, and T. Bellon, “NK cell recognition of non-classical HLA class I molecules,” Seminars in Immunology, vol. 12, no. 2, pp. 109–119, 2000. View at Publisher · View at Google Scholar · View at Scopus
  21. H. G. Ljunggren and K. Karre, “In search of the “missing self”: MHC molecules and NK cell recognition,” Immunology Today, vol. 11, no. 7, pp. 237–244, 1990. View at Google Scholar · View at Scopus
  22. C. Vilches and P. Parham, “KIR: diverse, rapidly evolving receptors of innate and adaptive immunity,” Annual Review of Immunology, vol. 20, pp. 217–251, 2002. View at Publisher · View at Google Scholar · View at Scopus
  23. C. A. Janeway Jr. and R. Medzhitov, “Innate immune recognition,” Annual Review of Immunology, vol. 20, pp. 197–216, 2002. View at Publisher · View at Google Scholar · View at Scopus
  24. M. R. Miller, J. Hankinson, V. Brusasco et al., “Standardisation of spirometry,” European Respiratory Journal, vol. 26, no. 2, pp. 319–338, 2005. View at Publisher · View at Google Scholar · View at Scopus
  25. C. Monaco, E. Andreakos, S. Kiriakidis, M. Feldmann, and E. Paleolog, “T-cell-mediated signalling in immune, inflammatory and angiogenic processes: the cascade of events leading to inflammatory diseases,” Current Drug Targets: Inflammation and Allergy, vol. 3, no. 1, pp. 35–42, 2004. View at Publisher · View at Google Scholar · View at Scopus
  26. M. Herrmann, R. E. Voll, and J. R. Kalden, “Etiopathogenesis of systemic lupus erythematosus,” Immunology Today, vol. 21, no. 9, pp. 424–426, 2000. View at Publisher · View at Google Scholar · View at Scopus
  27. P. K. Jeffery, “Structural and inflammatory changes in COPD: a comparison with asthma,” Thorax, vol. 53, no. 2, pp. 129–136, 1998. View at Google Scholar · View at Scopus
  28. M. G. Cosio and A. Guerassimov, “Chronic obstructive pulmonary disease: inflammation of small airways and lung parenchyma,” The American Journal of Respiratory and Critical Care Medicine, vol. 160, no. 5, part 2, pp. S21–S25, 1999. View at Google Scholar · View at Scopus
  29. C. A. Biron, “Initial and innate responses to viral infections—pattern setting in immunity or disease,” Current Opinion in Microbiology, vol. 2, no. 4, pp. 374–381, 1999. View at Publisher · View at Google Scholar · View at Scopus
  30. J. S. Orange, “Formation and function of the lytic NK-cell immunological synapse,” Nature Reviews Immunology, vol. 8, no. 9, pp. 713–725, 2008. View at Publisher · View at Google Scholar · View at Scopus
  31. C. Bordignon, F. Villa, A. Vecchi et al., “Natural cytotoxic activity in human lungs,” Clinical and Experimental Immunology, vol. 47, no. 2, pp. 437–444, 1982. View at Google Scholar · View at Scopus
  32. B. W. S. Robinson, P. Pinkston, and R. G. Crystal, “Natural killer cells are present in the normal human lung but are functionally impotent,” Journal of Clinical Investigation, vol. 74, no. 3, pp. 942–950, 1984. View at Google Scholar · View at Scopus
  33. F. J. Culley, “Natural killer cells in infection and inflammation of the lung,” Immunology, vol. 128, no. 2, pp. 151–163, 2009. View at Publisher · View at Google Scholar · View at Scopus
  34. J. Tanaka, Y. Tutumi, A. Mori et al., “Sequential analysis of HLA-C-specific killer cell inhibitory receptor (CD158b) expressing peripheral blood mononuclear cells during chronic graft-versus-host disease,” Bone Marrow Transplantation, vol. 26, no. 3, pp. 287–290, 2000. View at Google Scholar · View at Scopus
  35. A. Velardi, “Role of KIRs and KIR ligands in hematopoietic transplantation,” Current Opinion in Immunology, vol. 20, no. 5, pp. 581–587, 2008. View at Publisher · View at Google Scholar · View at Scopus
  36. N. Guerra, M. Guillard, E. Angevin et al., “Killer inhibitory receptor (CD158b) modulates the lytic activity of tumor-specific T lymphocytes infiltrating renal cell carcinomas,” Blood, vol. 95, no. 9, pp. 2883–2889, 2000. View at Google Scholar · View at Scopus
  37. X. Zhu, A. S. Gadgil, R. Givelber et al., “Peripheral T cell functions correlate with the severity of chronic obstructive pulmonary disease,” Journal of Immunology, vol. 182, no. 5, pp. 3270–3277, 2009. View at Publisher · View at Google Scholar · View at Scopus