Combination of Human Leukocyte Antigen and Killer Cell Immunoglobulin-Like Receptor Genetic Background Influences the Onset Age of Hepatocellular Carcinoma in Male Patients with Hepatitis B Virus Infection

Table 2

Effects of KIR genes and genotypes on the onset age of HCC by KM analysis.

KIR gene and genotype		𝑛 (%)	Median age	P value
2DL1	Negative	4 (2.3)	45	0.82
	Positive	167 (97.7)	50
2DL2	Negative	137 (80.1)	50	0.09
	Positive	34 (19.9))	49
2DL3	Negative	4 (2.3)	45	0.81
	Positive	167 (97.7))	50
2DL5	Negative	103 (60.2)	50	0.67
	Positive	68 (39.8)	50
3DL1	Negative	3 (1.8)	41	0.68
	Positive	168 (98.2)	50
2DS1	Negative	109 (63.7)	50	0.49
	Positive	62 (36.3)	49
2DS2	Negative	139 (81.3)	50	0.09
	Positive	32 (18.7)	50
2DS3	Negative	145 (84.8)	50	0.07
	Positive	26 (15.2)	49
2DS4(f)	Negative	28 (16.4)	49	0.83
	Positive	143 (83.6)	50
2DS4(d)	Negative	116 (67.8)	50	0.97
	Positive	55 (32.2)	49
2DS5	Negative	124 (72.5)	50	0.50
	Positive	47 (27.5)	51
3DS1	Negative	108 (63.2)	49	0.98
	Positive	63 (36.8)	50
KIR genotype	AA	84 (49.1)	50	0.42
	BX	87 (50.9)	50