Journal of Immunology Research

Research Article

Respiratory-Related Hospitalizations following Prophylaxis in the Canadian Registry for Palivizumab (2005–2012) Compared to Other International Registries

Cumulative patient demographics by prophylaxis indication (2005–2012).


	Premature	CLD	HSCHD	Other	Total	value

Male, (%)	4996 (57.1)	601 (57.3)	777 (55.0)	1161 (55.4)	7535 (56.6)	0.280
Caucasian, (%)	6031 (68.9)	750 (71.6)	1047 (74.0)	1538 (73.3)	9366 (70.4)	<0.0005
Daycare attendance, (%)	107 (1.2)	58 (5.5)	117 (8.3)	196 (9.3)	478 (3.6)	<0.0005
Atopy in the family, (%)	3390 (38.7)	471 (44.9)	610 (43.1)	920 (43.9)	5391 (40.5)	<0.0005
Mean enrolment age (mo ± SD)	3.3 ± 3.1	10.3 ± 7.3	8.7 ± 7.3	10.0 ± 8.9	5.5 ± 6.2	<0.0005
Mean gestational age (wk ± SD)	30.9 ± 3.3	30.5 ± 5.8	38.1 ± 10.6	35.6 ± 5.7	32.4 ± 5.8	<0.0005
Mean birth weight (g ± SD)	1590 ± 632	1628 ± 1132	3048 ± 1154	2583 ± 1390	1902 ± 1043	<0.0005
Mean enrolment weight (g ± SD)	4017 ± 2167	7047 ± 2510	6092 ± 4423	7258 ± 3257	5082 ± 3087	<0.0005
Multiple births, (%)	3140 (35.9)	250 (23.9)	89 (6.3)	340 (16.2)	3819 (28.7)	<0.0005
Mother that smokes, (%)	1259 (14.4)	163 (15.6)	197 (13.9)	260 (12.4)	1879 (14.1)	0.067
Mother smoked during pregnancy, (%)	1193 (13.6)	151 (14.4)	184 (13.0)	252 (12.0)	1780 (13.4)	0.188
Smoking in the household, (%)	2471 (28.2)	276 (26.3)	335 (23.7)	465 (22.2)	3547 (26.6)	<0.0005
≥2 smokers in the home, (%)	979 (11.2)	101 (9.6)	138 (9.8)	198 (9.4)	1416 (10.6)	0.042
Siblings, (%)	5384 (61.5)	658 (62.8)	791 (55.9)	1364 (65.0)	8197 (61.6)	<0.0005
Siblings in daycare, (%)	1588 (18.1)	153 (14.6)	242 (17.1)	451 (21.5)	2434 (18.3)	<0.0005
≥5 people in the household, (%)	2509 (28.7)	238 (22.7)	299 (21.1)	505 (24.1)	3551 (26.7)	<0.0005

HSCHD: hemodynamically significant congenital heart disease; CLD: chronic lung disease.