Journal of Immunology Research / 2013 / Article / Fig 3

Research Article

An Imbalance between Frequency of CD4+CD25+FOXP3+ Regulatory T Cells and CCR4+ and CCR9+ Circulating Helper T Cells Is Associated with Active Perennial Allergic Conjunctivitis

Figure 3

Frequency of CD25+ cells and CD4+CD25+FOXP3+ regulatory T cells after stimulation. (a) Representative dot plots of PBMC stimulated with Der p or Con A in patients with PAC. (b) Comparative histograms of FOXP3+ frequency on CD4+CD25+ gated cells. The -axis denotes the mean fluorescence intensity (MFI) of FOXP3. (c) Significant differences were observed in the frequency of Tregs upon Der p-stimulation. (d) Distribution of FOXP3+ and FOXP3− cell subsets on CD4+CD25+ gated cells after allergen-stimulation.

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