Rapamycin Ameliorates Proteinuria and Restores Nephrin and Podocin Expression in Experimental Membranous Nephropathy
Figure 4
Electron microscopy. (a) Passive Heymann Nephritis. Massive subepithelial deposits (white arrow) with severe fusion of podocyte foot processes; original magnification ×12 k. (b) Passive Heymann Nephritis. Subepithelial deposits in higher magnification (white arrows); original magnification ×26 k. (c) Passive Heymann Nephritis after rapamycin administration. The deposits and the podocytic injury were attenuated compared to the PHN group; original magnification ×8 k. (d) Passive Heymann Nephritis after rapamycin administration (higher magnification ×20 k). Small subepithelial deposit (white arrow).