Research Article

Glioma-Associated Antigen HEATR1 Induces Functional Cytotoxic T Lymphocytes in Patients with Glioma

Table 1

Clinical characteristics of healthy donors and patients.

NumberGenderYearsTumor locationPathologyGradeELISpot responseHLA-A2

198M54HealthyNegativeYes
203M55HealthyNegativeYes
205F56HealthyNegativeYes
209F45HealthyNegativeYes
219M22HealthyNegativeNo
306M31HealthyNegativeNo

215F48Right frontalMeningioma0NegativeYes
216F62CerebellumHemangioblastoma0NegativeNo
255F59Left frontalMeningioma0NegativeYes
226F49Sellar regionPituitary adenoma0NegativeYes
261M21Sellar regionPituitary adenoma0NegativeNo

122M45Right temporal Astrocytoma2NegativeNo
135F37Right temporal Astrocytoma2NegativeYes
217M48Right frontal Astrocytoma2NegativeNo
246F30Left parietalAstrocytoma2NegativeYes
252M50Right temporalOligodendroglioma2NegativeNo
264M45Right frontal-callosumAstrocytoma2NegativeYes
262M40Left temporalOligodendroglioma2NegativeYes

218M58Right temporalAA3NegativeYes
238F56Right callosal convolution AO3NegativeNo
254F33Right frontalAOA3NegativeYes
256F46Right temporal-basal gangliaAA3NegativeNo
259F58Right parietalAO3NegativeNo
265M56Right frontal-parietal AOA3NegativeNo
127F42Left frontalAA3PositiveNo
140M45Left temporalAA3PositiveA0201/A1101
156M48Left occipitalAE3PositiveA0203/A3001
239M16Left temporalAA3PositiveA0207/A1102

129F38Left occipitalGBM4NegativeYes
133F48Left temporalGBM4NegativeNo
147F61Left temporalGBM4NegativeYes
150M48Right frontal-temporalGBM4NegativeYes
151M30Right temporalGBM4NegativeYes
214M66Right parietal-occipitalGBM4NegativeNo
223M37Left frontal-temporal GBM4NegativeYes
224M59Left temporal-occipitalGBM4NegativeYes
225M31Left frontal GBM4NegativeNo
231M36Left frontalGBM4NegativeNo
241M58Right frontal GBM4NegativeYes
253M54Left frontalGBM4NegativeNo
132M68Right temporalGBM4PositiveA0201/A0203
141F12Right parietal-occipital GBM4PositiveNo
220M47Left temporalGBM4PositiveA0201/A3303
221F39Right temporalGBM4PositiveNo

: recurrence; F: female; M: male; GBM: glioblastoma multiforme; AA: anaplastic astrocytoma; AO: anaplastic oligodendroglioma; AOA: anaplastic oligoastrocytoma; AE: anaplastic ependymoma.