Review Article

Novel Clinical and Diagnostic Aspects of Antineutrophil Cytoplasmic Antibodies

Table 1

Agreement between a new PR3 CLIA assay and an established high sensitivity PR3 assay. Spearman’s rho of results was found at 0.74 (95% CI 0.67–0.80, data not shown) [65].

All patients ( )ELIA PR3sPercent agreement
(95% confidence)
PositiveNegativeTotal

PR3 CLIA
 Positive45348Pos. Agree = 86.5 (74.2–94.4%)
 Negative7141148Neg. Agree = 97.9 (94.0–99.6%)
 Total52144196Total Agree = 94.9 (90.8–97.5%)