Tribbles 3 Regulates the Fibrosis Cytokine TGF-β1 through ERK1/2-MAPK Signaling Pathway in Diabetic Nephropathy
Figure 3
Effect of high glucose (HG) on TRB3 mRNA and protein levels in murine mesangial cells (MMCs) over time. MMCs were cultured in media containing NG and then stimulated with NG + high mannitol (HM) or HG for 6, 12, 24, and 48 h. (a) RT-PCR analysis of the mRNA level of TRB3. (b) Western blot analysis of the protein level of TRB3. Data are mean ± SEM. , versus NG.
