Gαs Protein Expression Is an Independent Predictor of Recurrence in Prostate Cancer

Figure 2

Kaplan-Meier analysis of overall survival (cumulative survival) and PSA progression-free survival of PCa patients relative to Gαs expression. (a) Correlation of Gαs expression with overall survival; (b) in metastatic PCa specimens, the correlation of Gαs expression with overall survival; (c) in localized PCa specimens, the correlation of Gαs expression with overall survival; (d) correlation of Gαs expression with PSA-free survival; (e) in metastatic PCa specimens, the correlation of Gαs expression with PSA-free survival; (f) in localized PCa specimens, the correlation of Gαs expression with PSA-free survival. A statistically significant difference is shown in overall survival and PSA progression-free survival outcome between the different groups of patients, with those having positive expression of Gαs having the better overall survival and PSA progression-free survival.