Research Article
Autoantibodies Targeting AT1 Receptor from Patients with Acute Coronary Syndrome Upregulate Proinflammatory Cytokines Expression in Endothelial Cells Involving NF-κB Pathway
Figure 5
Effects of valsartan and PDTC on AT1-AAs or angiotensin II-induced protein expression in human endothelial cells. Valsartan (AT1 receptor blocker) and PDTC (NF-κB inhibitor) were added to cell medium 2 hours before AT1-AAs treatment for 12 hours. Panel (a) shows the typical Western blot results. Panel (b) shows the summarized data (); versus control group (lane 1); versus AT1-AAs group (lane 3).
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