Analytical and Clinical Comparison of Two Fully Automated Immunoassay Systems for the Diagnosis of Celiac Disease
(a) Venn diagram depiction of clinical sensitivity and specificity as well as assay agreement for tTG IgA/IgG and DGP IgA/IgG assays. Upper circle in each group represents all 74 patients with celiac disease and shows presence/overlap of markers (b) Cluster analysis. The cluster analysis shows that the majority of celiac disease patients have multiple positive results. Some of the controls also show positive results by different methods. Isolated vertical lines indicate specimens positive for multiple markers and potentially at increased risk for celiac disease. Red: positive; black: negative; grey: no data available.
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