Sonic Hedgehog Signaling Drives Proliferation of Synoviocytes in Rheumatoid Arthritis: A Possible Novel Therapeutic Target
Figure 3
Positive expression rates of Shh-related proteins in synovium from RA patients and controls. The positive expression rate of Shh, Smo, and Gli1 protein in synovium of RA patients was higher than that in the control group, while there was no difference in the expression of Ptch1. versus control. The positive expression rate is defined as (number of positive cells/total cells) × 100%.
