Table of Contents Author Guidelines Submit a Manuscript
Journal of Immunology Research
Volume 2014, Article ID 515984, 12 pages
http://dx.doi.org/10.1155/2014/515984
Research Article

Parainfluenza Virus Type 1 Induces Epithelial IL-8 Production via p38-MAPK Signalling

Department of Virology and Mycology Research, National Institute of Respiratory Diseases “Ismael Cosio Villegas”, Calzada de Tlalpan 4502, Colonia Sección XVI, Delegación Tlalpan, 14080 México, DF, Mexico

Received 12 December 2013; Revised 11 May 2014; Accepted 23 May 2014; Published 11 June 2014

Academic Editor: Michael H. Kershaw

Copyright © 2014 Miguel Ángel Galván Morales et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. H. Schomacker, A. Schaap-Nutt, P. L. Collins, and A. C. Schmidt, “Pathogenesis of acute respiratory illness caused by human parainfluenza viruses,” Current Opinion in Virology, vol. 2, no. 3, pp. 294–299, 2012. View at Publisher · View at Google Scholar · View at Scopus
  2. C. B. Hall, “Respiratory syncytial virus and parainfluenza virus,” The New England Journal of Medicine, vol. 344, no. 25, pp. 1917–1928, 2001. View at Publisher · View at Google Scholar · View at Scopus
  3. M. E. Manjarrez, E. Montufar, D. P. Rosete, R. Chapela, I. Calderón, and J. Villalba, “Infección en pacientes con inflamación y enfermedad pulmonar obstructiva crónica o asma,” Revista del Instituto Nacional de Enfermedades Respiratorias, vol. 12, no. 2, pp. 101–106, 1999. View at Google Scholar
  4. M. E. Manjarrez, D. P. Rosete, M. Rincón, J. Villalba, A. Cravioto, and R. Cabrera, “Comparative viral frequency in Mexican children under 5 years of age with and without upper respiratory symptoms,” Journal of Medical Microbiology, vol. 52, no. 7, pp. 579–583, 2003. View at Publisher · View at Google Scholar · View at Scopus
  5. A. Marx, T. J. Torok, R. C. Holman, M. J. Clarke, and L. J. Anderson, “Pediatric hospitalizations for croup (laryngotracheobronchitis): biennial increases associated with human parainfluenza virus 1 epidemics,” Journal of Infectious Diseases, vol. 176, no. 6, pp. 1423–1427, 1997. View at Google Scholar · View at Scopus
  6. M. E. Counihan, D. K. Shay, R. C. Holman, S. A. Lowther, and L. J. Anderson, “Human parainfluenza virus-associated hospitalizations among children less than five years of age in the United States,” Pediatric Infectious Disease Journal, vol. 20, no. 7, pp. 646–653, 2001. View at Publisher · View at Google Scholar · View at Scopus
  7. M. Dobrovoljac and G. C. Geelhoed, “How fast does oral dexamethasone work in mild to moderately severe croup? A randomized double-blinded clinical trial,” Emergency Medicine Australasia, vol. 24, no. 1, pp. 79–85, 2012. View at Publisher · View at Google Scholar · View at Scopus
  8. M. G. Ottolini, D. D. Porter, J. C. G. Blanco, and G. A. Prince, “A cotton rat model of human parainfluenza 3 laryngotracheitis: virus growth, pathology, and therapy,” Journal of Infectious Diseases, vol. 186, no. 12, pp. 1713–1717, 2002. View at Publisher · View at Google Scholar · View at Scopus
  9. J. D. Cherry, “State of the evidence for standard-of-care treatments for croup: are we where we need to be?” The Pediatric Infectious Disease Journal, vol. 24, no. 11, pp. S198–S201, 2005. View at Google Scholar · View at Scopus
  10. M. Yoshizumi, H. Kimura, Y. Okayama et al., “Relationships between cytokine profiles and signaling pathways (IκB kinase and p38 MAPK) in parainfluenza virus-infected lung fibroblasts,” Frontiers in Microbiology, vol. 1, article 124, 2010. View at Publisher · View at Google Scholar · View at Scopus
  11. K. Parhar, A. Ray, U. Steinbrecher, C. Nelson, and B. Salh, “The p38 mitogen-activated protein kinase regulates interleukin-1β-induced IL-8 expression via an effect on the IL-8 promoter in intestinal epithelial cells,” Immunology, vol. 108, no. 4, pp. 502–512, 2003. View at Publisher · View at Google Scholar · View at Scopus
  12. X. Li, D. Liang, X. Lin, E. S. Robertson, and K. Lan, “Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen reduces interleukin-8 expression in endothelial cells and impairs neutrophil chemotaxis by degrading nuclear p65,” Journal of Virology, vol. 85, no. 17, pp. 8606–8615, 2011. View at Publisher · View at Google Scholar · View at Scopus
  13. A. K. J. Chan, J. M. Langley, and J. C. LeBlanc, “Interobserver variability of croup scoring in clinical practice,” Paediatrics and Child Health, vol. 6, no. 6, pp. 347–351, 2001. View at Google Scholar · View at Scopus
  14. J. F. Bermejo-Martin, D. Bernardo, M. Dominguez-Gil et al., “Interleukin (IL)-1β, IL-6 and IL-8 in nasal secretions: a common role for innate immunity in viral bronchial infection in infants?” The British Journal of Biomedical Science, vol. 63, no. 4, pp. 173–175, 2006. View at Google Scholar · View at Scopus
  15. R. Garofalo, M. Sabry, M. Jamaluddin et al., “Transcriptional activation of the interleukin-8 gene by respiratory syncytial virus infection in alveolar epithelial cells: nuclear translocation of the RelA transcription factor as a mechanism producing airway mucosal inflammation,” Journal of Virology, vol. 70, no. 12, pp. 8773–8781, 1996. View at Google Scholar · View at Scopus
  16. M. Z. Norzila, K. Fakes, R. L. Henry, J. Simpson, and P. G. Gibson, “Interleukin-8 secretion and neutrophil recruitment accompanies induced sputum eosinophil activation in children with acute asthma,” The American Journal of Respiratory and Critical Care Medicine, vol. 161, no. 3, pp. 769–774, 2000. View at Google Scholar · View at Scopus
  17. D. S. Bischoff, J.-H. Zhu, N. S. Makhijani, and D. T. Yamaguchi, “Acidic pH stimulates the production of the angiogenic CXC chemokine, CXCL8 (interleukin-8), in human adult mesenchymal stem cells via the extracellular signal-regulated kinase, p38 mitogen-activated protein kinase, and NF-κB pathways,” Journal of Cellular Biochemistry, vol. 104, no. 4, pp. 1378–1392, 2008. View at Publisher · View at Google Scholar · View at Scopus
  18. R. Arnold, B. Humbert, H. Werchau, H. Gallati, and W. Konig, “Interleukin-8, interleukin-6, and soluble tumour necrosis factor receptor type release from a human pulmonary epithelial cell line (A549) exposed to respiratory syncytial virus,” Immunology, vol. 82, no. 1, pp. 126–133, 1994. View at Google Scholar · View at Scopus
  19. N. Desloges, C. Schubert, M. H. Wolff, and M. Rahaus, “Varicella-zoster virus infection induces the secretion of interleukin-8,” Medical Microbiology and Immunology, vol. 197, no. 3, pp. 277–284, 2008. View at Publisher · View at Google Scholar · View at Scopus
  20. B. König, T. Krusat, H. J. Streckert, and W. König, “IL-8 release from human neutrophils by the respiratory syncytial virus is independent of viral replication,” Journal of Leukocyte Biology, vol. 60, no. 2, pp. 253–260, 1996. View at Google Scholar · View at Scopus
  21. D. J. Hall, M. E. Bates, L. Guar, M. Cronan, N. Korpi, and P. J. Bertics, “The role of p38 MAPK in rhinovirus-induced monocyte chemoattractant protein-1 production by monocytic-lineage cells,” Journal of Immunology, vol. 174, no. 12, pp. 8056–8063, 2005. View at Google Scholar · View at Scopus
  22. A. A. Andrade, P. N. G. Silva, A. C. T. C. Pereira et al., “The vaccinia virus-stimulated mitogen-activated protein kinase (MAPK) pathway is required for virus multiplication,” Biochemical Journal, vol. 381, no. 2, pp. 437–446, 2004. View at Publisher · View at Google Scholar · View at Scopus
  23. S. L. Johnston, A. Papi, P. J. Bates, J. G. Mastronarde, M. M. Monick, and G. W. Hunninghake, “Low grade rhinovirus infection induces a prolonged release of IL-8 in pulmonary epithelium,” Journal of Immunology, vol. 160, no. 12, pp. 6172–6181, 1998. View at Google Scholar · View at Scopus
  24. I. S. Lukashevich, R. Maryankova, A. S. Vladyko et al., “Lassa and Mopeia virus replication in human monocytes/macrophages and in endothelial cells: different effects on IL-8 and TNF-alpha gene expression,” Journal of Medical Virology, vol. 59, no. 4, pp. 552–560, 1999. View at Google Scholar
  25. J. L. Booth, K. M. Coggeshall, B. E. Gordon, and J. P. Metcalf, “Adenovirus type 7 induces interleukin-8 in a lung slice model and requires activation of Erk,” Journal of Virology, vol. 78, no. 8, pp. 4156–4164, 2004. View at Publisher · View at Google Scholar · View at Scopus
  26. R. J. Davis, “The mitogen-activated protein kinase signal transduction pathway,” Journal of Biological Chemistry, vol. 268, no. 20, pp. 14553–14556, 1993. View at Google Scholar · View at Scopus
  27. L. Chang and M. Karin, “Mammalian MAP kinase signalling cascades,” Nature, vol. 410, no. 6824, pp. 37–40, 2001. View at Publisher · View at Google Scholar · View at Scopus
  28. C. Dong, R. J. Davis, and R. A. Flavell, “MAP kinases in the immune response,” Annual Review of Immunology, vol. 20, pp. 55–72, 2002. View at Publisher · View at Google Scholar · View at Scopus
  29. R. Wahid, M. J. Cannon, and M. Chow, “Virus-specific CD4+ and CD8+ cytotoxic T-cell responses and long-term T-cell memory in individuals vaccinated against polio,” Journal of Virology, vol. 79, no. 10, pp. 5988–5995, 2005. View at Publisher · View at Google Scholar · View at Scopus
  30. D. H. Clarke and J. Casals, “Techniques for hemagglutination and hemagglutination-inhibition with arthropod-borne viruses,” The American Journal of Tropical Medicine and Hygiene, vol. 7, no. 5, pp. 561–573, 1958. View at Google Scholar · View at Scopus
  31. E. Trybala, B. Svennerholm, T. Bergstrom, S. Olofsson, S. Jeansson, and J. L. Goodman, “Herpes simplex virus type 1-induced hemagglutination: glycoprotein C mediates virus binding to erythrocyte surface heparan sulfate,” Journal of Virology, vol. 67, no. 3, pp. 1278–1285, 1993. View at Google Scholar · View at Scopus
  32. W. Wiriyarat, H. Lerdsamran, P. Pooruk et al., “Erythrocyte binding preference of 16 subtypes of low pathogenic avian influenza and 2009 pandemic influenza A (H1N1) viruses,” Veterinary Microbiology, vol. 146, no. 3-4, pp. 346–349, 2010. View at Publisher · View at Google Scholar · View at Scopus
  33. L. Kittigul, S. Suthachana, C. Kittigul, and V. Pengruangrojanachai, “Immunoglobulin M-capture biotin-streptavidin enzyme-linked immunosorbent assay for detection of antibodies to dengue viruses,” The American Journal of Tropical Medicine and Hygiene, vol. 59, no. 3, pp. 352–356, 1998. View at Google Scholar · View at Scopus
  34. Y. M. Zhu, S. J. Webster, D. Flower, and P. J. Woll, “Interleukin-8/CXCL8 is a growth factor for human lung cancer cells,” The British Journal of Cancer, vol. 91, no. 11, pp. 1970–1976, 2004. View at Publisher · View at Google Scholar · View at Scopus
  35. U. K. Laemmli, “Cleavage of structural proteins during the assembly of the head of bacteriophage T4,” Nature, vol. 227, no. 5259, pp. 680–685, 1970. View at Publisher · View at Google Scholar · View at Scopus
  36. S. Matsukura, F. Kokubu, H. Noda, H. Tokunaga, and M. Adachi, “Expression of IL-6, IL-8, and RANTES on human bronchial epithelial cells, NCI-H292, induced by influenza virus A,” Journal of Allergy and Clinical Immunology, vol. 98, no. 6, pp. 1080–1087, 1996. View at Publisher · View at Google Scholar · View at Scopus
  37. W. Chen, M. M. Monick, A. B. Carter, and G. W. Hunninghake, “Activation of ERK2 by respiratory syncytial virus in A549 cells is linked to the production of interleukin 8,” Experimental Lung Research, vol. 26, no. 1, pp. 13–26, 2000. View at Google Scholar · View at Scopus
  38. S. J. Ajizian, B. K. English, and E. A. Meals, “Specific inhibitors of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways block inducible nitric oxide synthase and tumor necrosis factor accumulation in murine macrophages stimulated with lipopolysaccharide and interferon-γ,” Journal of Infectious Diseases, vol. 179, no. 4, pp. 939–944, 1999. View at Publisher · View at Google Scholar · View at Scopus
  39. A. Kalmes, J. Deou, A. W. Clowes, and G. Daum, “Raf-1 is activated by the p38 mitogen-activated protein kinase inhibitor, SB203580,” FEBS Letters, vol. 444, no. 1, pp. 71–74, 1999. View at Publisher · View at Google Scholar · View at Scopus
  40. V. A. Young, P. J. Dillon, and G. D. Parks, “Variants of the Paramyxovirus Simian virus 5 with accelerated or delayed viral gene expression activate proinflammatory cytokine synthesis,” Virology, vol. 350, no. 1, pp. 90–102, 2006. View at Publisher · View at Google Scholar · View at Scopus
  41. K. J. Henrickson, “Parainfluenza viruses,” Clinical Microbiology Reviews, vol. 16, no. 2, pp. 242–264, 2003. View at Publisher · View at Google Scholar · View at Scopus
  42. Y. Matsuoka, J. Curran, T. Pelet, D. Kolakofsky, R. Ray, and R. W. Compans, “The P gene of human parainfluenza virus type 1 encodes P and C proteins but not a cysteine-rich V protein,” Journal of Virology, vol. 65, no. 6, pp. 3406–3410, 1991. View at Google Scholar · View at Scopus
  43. C. Ah-Tye, S. Schwartz, K. Huberman, E. Carlin, and A. Moscona, “Virus-receptor interactions of human parainfluenza viruses types 1, 2 and 3,” Microbial Pathogenesis, vol. 27, no. 5, pp. 329–336, 1999. View at Publisher · View at Google Scholar · View at Scopus
  44. K. J. Henrickson and L. L. Savatski, “Antigenic structure, function, and evolution of the hemagglutinin-neuraminidase protein of human parainfluenza virus type 1,” Journal of Infectious Diseases, vol. 176, no. 4, pp. 867–875, 1997. View at Google Scholar · View at Scopus
  45. X. Yang, Y. Chen, and D. Gabuzda, “ERK MAP kinase links cytokine signals to activation of latent HIV-1 infection by stimulating a cooperative interaction of AP-1 and NF-κB,” Journal of Biological Chemistry, vol. 274, no. 39, pp. 27981–27988, 1999. View at Publisher · View at Google Scholar · View at Scopus
  46. K. K. Rittichier, “The role of corticosteroids in the treatment of croup,” Treatments in Respiratory Medicine, vol. 3, no. 3, pp. 139–145, 2004. View at Publisher · View at Google Scholar · View at Scopus
  47. E. Irusen, J. G. Matthews, A. Takahashi, P. J. Barnes, K. F. Chung, and I. M. Adcock, “p38 mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: role in steroid-insensitive asthma,” Journal of Allergy and Clinical Immunology, vol. 109, no. 4, pp. 649–657, 2002. View at Publisher · View at Google Scholar · View at Scopus