Parainfluenza Virus Type 1 Induces Epithelial IL-8 Production via p38-MAPK Signalling

Table 2

IL-8 production (pg/mL) in infected HEp-2 cells treated with ERK1/2, JNK, and p38 kinase inhibitors.

Time	ERK1/2	JNK	P38	Uninfected cells	SD	SEM	Chi square	𝑃	CV
45′	41.88^a	43.71^a	0.06^b	50.04^a	20.94	6.04	8.74	0.03	61.71
60′	102.16^a	95.27^a	11.10^c	92.48^b	75.26	11.25	9.46	0.02	51.78
90′	139.25^a	143.91^a	39.73^b	135.85^a	45.51	13.14	8.43	0.03	39.68
120′	179.71^a	169.71^a	59.48^b	181.99^a	54.30	15.68	7.61	0.05	36.75
12 hours	243.08^a	240.05^a	152.78^b	246.07^a	41.33	11.93	6.58	0.08	18.74
24 hours	136.39^ab	144.50^a	129.51^b	137.07^ab	6.50	1.88	7.46	0.05	4.74

a,b,cMeans with no common superscript in a row differ (𝑃<0.05). SD: standard deviation; SEM: standard error of the mean; 𝑃: probability value; CV: coefficient of variation.