Research Article
Insight into Gene Polymorphisms Involved in Toll-Like Receptor/Interferon Signalling Pathways for Systemic Lupus Erythematosus in South East Asia
Table 5
Association of each SNP with the Malaysian SLE, resulting from combined analysis of the three ethnicities.
| Gene | SNP | Minor allele | OR (95% CI) | P-value (Bonferroni adjusted) |
| STAT4 | rs7574865 | T | 1.337 (0.948–1.885) | 0.686 | rs10168266 | T | 1.435 (1.143–1.802) | 0.014* | rs7601754 | G | 0.800 (0.589–1.085) | NA |
| TNFAIP3 | rs2230926 | G | 0.522 (0.273–0.999) | 0.350 | rs3757173 | C | 1.660 (1.088–2.531) | 0.133 |
| IRF5 | rs4728142 | A | 1.272 (0.934–1.733) | 0.889 | rs729302 | C | 0.947 (0.768–1.168) | NA |
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