Research Article

Insight into Gene Polymorphisms Involved in Toll-Like Receptor/Interferon Signalling Pathways for Systemic Lupus Erythematosus in South East Asia

Table 5

Association of each SNP with the Malaysian SLE, resulting from combined analysis of the three ethnicities.

GeneSNPMinor alleleOR (95% CI)P-value (Bonferroni adjusted)

STAT4 rs7574865T1.337 (0.948–1.885)0.686
rs10168266T1.435 (1.143–1.802)0.014*
rs7601754G0.800 (0.589–1.085)NA

TNFAIP3 rs2230926G0.522 (0.273–0.999)0.350
rs3757173C1.660 (1.088–2.531)0.133

IRF5 rs4728142A1.272 (0.934–1.733)0.889
rs729302C0.947 (0.768–1.168)NA

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