The Many Faces of Human Leukocyte Antigen-G: Relevance to the Fate of Pregnancy

Figure 1

Polymorphisms in the 3′-untranslated region (3′UTR) of the HLA-G gene. The 3′UTR haplotype shown below has been associated with the risk of developing severe preeclampsia [25]. (Nomenclature used by different authors is shown for clarification. “SNPxxxx,” for example, SNP3127, is based on the original publication of the HLA-G gene sequence by Geraghty et al. [26] and the study of HLA-G 3′UTR haplotypes in cases of severe preeclampsia by Larsen et al. [25]; “+xxxx,” for example, +3142, by the publication by Castelli et al. [27]. (Based on [25, 27, 28])).