Review Article
The Many Faces of Human Leukocyte Antigen-G: Relevance to the Fate of Pregnancy
Table 1
A comparison of differences in HLA-G gene and protein expression and functional characteristics between the 14 bp deletion and 14 bp insertion alleles. The observed differences may be influenced by other DNA and mRNA polymorphisms in the 3′-untranslated region (3′UTR), especially the +3142 and +3187 SNPs, and/or the 5′-upstream regulatory region of HLA-G that are in linkage disequilibrium with the 14 bp ins/del polymorphism (see the text and Figure 1 for details). (Based on a large number of references listed in the text).
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Only one or very few studies; needs further verification. 2-microglobulin-associated soluble HLA-G1 and HLA-G5. |