Effects of Pristane Alone or Combined with Chloroquine on Macrophage Activation, Oxidative Stress, and Th1/Th2 Skewness

Figure 1

Hemophagocytosis, extramedullary hematopoiesis, and macrophage infiltration in liver and spleen. Hemophagocytosis (arrow), extramedullary hematopoiesis (arrow head) in liver and spleen were illustrated by HE staining ((a), (b)). The distribution and expression of F4/80 in liver and spleen were depicted with immunohistochemistry ((c), (d)) and western blotting (e), respectively. ×200; inset, ×400. CQ: chloroquine. Results were expressed as mean ± SE for eight animals. ^∗𝑃<0.05 versus corresponding control mice, ^#𝑃<0.05 versus mice exposed to pristane for 12 weeks.

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