Clinical Study

Renal Transplantation Dramatically Reduces IgA Anti-beta-2-glycoprotein I Antibodies in Patients with Endstage Renal Disease

Table 1

Etiology of endstage renal disease.

DiseasePatients ( /%)IgA aB2GPI positive* valueIgA aB2GPI (U/mL)** value

Blood donors2203 (1.4%)
Diabetic nephropathy 68 (23.6%)24 (35.2%)<0.0001 <0.0001
Glomerular disease50 (16.0%)8 (16.0%)<0.0001 0.0001
 Non-IgA glomerulonephritis31 (10.7%)2 (6.4%)0.1165 0.1951
 Berger's disease (IgA nephritis)19 (6.5%)6 (31.5%)<0.0001 <0.0001
Nephroangiosclerosis 26 (9%)10 (38.4%)<0.0001 <0.0001
Systemic lupus erythematosus5 (1.7%)1 (20%)0.0865 0.2926
Interstitial nephritis 14 (4.8%)3 (21.4%)0.0003 <0.0001
Polycystic kidney disease 31 (10.7%)6 (19.3%)<0.0001 <0.0001
Others (obstructive, metabolic, and others)65 (22.5%)19 (29.2%)<0.0001 <0.0001
Undetermined 29 (10%)10 (34.4%)<0.0001 <0.0001

Number of patients; **mean ± standard error.