Clinical Study
Renal Transplantation Dramatically Reduces IgA Anti-beta-2-glycoprotein I Antibodies in Patients with Endstage Renal Disease
Table 1
Etiology of endstage renal disease.
| Disease | Patients (/%) | IgA aB2GPI positive* | value | IgA aB2GPI (U/mL)** | value |
| Blood donors | 220 | 3 (1.4%) | | | | Diabetic nephropathy | 68 (23.6%) | 24 (35.2%) | <0.0001 | | <0.0001 | Glomerular disease | 50 (16.0%) | 8 (16.0%) | <0.0001 | | 0.0001 | Non-IgA glomerulonephritis | 31 (10.7%) | 2 (6.4%) | 0.1165 | | 0.1951 | Berger's disease (IgA nephritis) | 19 (6.5%) | 6 (31.5%) | <0.0001 | | <0.0001 | Nephroangiosclerosis | 26 (9%) | 10 (38.4%) | <0.0001 | | <0.0001 | Systemic lupus erythematosus | 5 (1.7%) | 1 (20%) | 0.0865 | | 0.2926 | Interstitial nephritis | 14 (4.8%) | 3 (21.4%) | 0.0003 | | <0.0001 | Polycystic kidney disease | 31 (10.7%) | 6 (19.3%) | <0.0001 | | <0.0001 | Others (obstructive, metabolic, and others) | 65 (22.5%) | 19 (29.2%) | <0.0001 | | <0.0001 | Undetermined | 29 (10%) | 10 (34.4%) | <0.0001 | | <0.0001 |
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Number of patients; **mean ± standard error.
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