Efficacy of Primate Humoral Passive Transfer in a Murine Model of Pneumonic Plague Is Mouse Strain-Dependent
Figure 7
Hsd:NIHS mice had better survival outcomes than BALB/c mice after administration of human serum. Study (5), mice per group. Mice were injected with 250 μL human serum into the peritoneal cavity, 3–6 hours before being exposed to aerosolised Y. pestis using a modified contained Henderson apparatus. The MTD was calculated using a Kaplan-Meier survival plot.
