Efficacy of Primate Humoral Passive Transfer in a Murine Model of Pneumonic Plague Is Mouse Strain-Dependent

<table>Passive immune therapy with NHP serum provided better protection in Hsd:NIHS mice than human serum after a lethal challenge of<i> Y. pestis. </i>Study (6), <svg height="11.125" id="M31" style="vertical-align:-0.17555pt" version="1.1" viewbox="0 0 44.400002 11.125" width="44.400002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> mice per group. Mice were administered 250 <i>μ</i>L serum into the peritoneal cavity, 3–6 hours before being exposed to aerosolised<i> Y. pestis</i> using a modified contained Henderson apparatus. The MTD was calculated using a Kaplan-Meier survival plot.</table>

Journal of Immunology Research

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Figure 9

Figure 9: Efficacy of Primate Humoral Passive Transfer in a Murine Model of Pneumonic Plague Is Mouse Strain-Dependent 