Research Article

Targeted Inhibition of mTOR Signaling Improves Sensitivity of Esophageal Squamous Cell Carcinoma Cells to Cisplatin

Table 3

Effects of mTOR siRNA and cisplatin alone or combined on growth of human ESCC xenograft in nude mice ( ).

GroupAnimal weightTumor volume at beginning1Tumor volume at terminationInhibition rate of tumor (%)

Control ā€”
siRNA 58.27
cis 63.18
siRNA + cis 76.70

Tumor volume is expressed as mm3. , compared to control group.