Immune Imbalance in Nasal Polyps of Caucasian Chronic Rhinosinusitis Patients Is Associated with a Downregulation of E-Selectin
Figure 2
Scatter plots of CD31 and adhesion molecule expression in nasal polyps compared to associated inferior turbinates using qPCR. Each single dot shows the relative expression of the target molecule in nasal polyps compared to associated inferior turbinates of one patient and median is indicated as horizontal bar. (a) CD31 is not differentially expressed (0.93-fold, ) between nasal polyps and inferior turbinates; (b) adhesion molecule expression in nasal polyps normalized to CD31. E-selectin (0.22-fold, ), P-selectin (1.82-fold, ), PSGL1 (1.29-fold, ), ICAM1 (0.93-fold, ), and VCAM1 (1.56-fold, ). (c) Adhesion molecule expression in nasal polyps normalized to β-actin. E-selectin (0.31-fold, ), P-selectin (1.97-fold, ), PSGL1 (1.34-fold, ), ICAM1 (1.28-fold, ), and VCAM1 (1.08-fold, ). CD31 normalized data differ insignificantly compared to the β-actin normalized data.
