Endothelin Receptors Expressed by Immune Cells Are Involved in Modulation of Inflammation and in Fibrosis: Relevance to the Pathogenesis of Systemic Sclerosis

Table 2

ET_A and ET_B expression on T lymphocytes and monocytes in relation to the clinical features of the disease, such as cutaneous form and presence or absence of PAH, ILD, and DUs.

	T lymphocytes		Monocytes
	ETA	ETB	ETA	ETB
lSSc ()/dSSc ()	99.1 ± 42.1/94.8 ± 48.2	51.9 ± 31.1/28.6 ± 17.9; ()	199.3 ± 34.5/251.2 ± 16.3	97.2 ± 24.5/74.4 ± 29.6; ()
PAH presence/absence	102.6 ± 45.3/104.7 ± 40.9	47.2 ± 26.8/44.9 ± 30.1	202.7 ± 31.4/200.8 ± 30.9	77.2 ± 23.4/96.9 ± 27.3
ILD presence/absence	111.6 ± 43.9/77.8 ± 34.2; ()	44.8 ± 27.3/45.3 ± 21.6	199.8 ± 56.5/211.2 ± 47.3	90.6 ± 26.5/89.7 ± 31.7
DUs presence/absence	121.4 ± 69/98.8 ± 41.6	40.8 ± 20.1/48.6 ± 31	221 ± 4.3/196.2 ± 69.6	80.4 ± 25.3/93.6 ± 27.5