Research Article

Analysis of a Functional IL-6 Gene Polymorphism in HLAB27 Associated and Intermediate Uveitis Gives New Insight in Disease Pathogenesis and Commonality with Other Autoimmune Diseases

Table 1

Distribution of the investigated gene polymorphisms in patients and controls.

HLAB27 AAUIUHLAB27 negative controlsHLAB27 positive controlsControls combined
( = 134)( = 84)( = 132)( = 65)( = 197)

rs1800795
 G/G40 (29.9%)19 (22.6%)51 (38.6%)24 (36.9%)75 (38.1%)
 G/C76 (56.7%)50 (59.5%)62 (47.0%)31 (47.7%)93 (47.2%)
 C/C18 (13.4%)15 (17.9%)19 (14.4%)10 (15.4%)29 (14.7%)

AAU: acute anterior uveitis.
IU: intermediate uveitis.